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Date of Award
Restricted Thesis: Campus only access
Bachelor of Science
3-Dimethylamino-2-arylacrylic acid esters, 3-dimethylamino-2-aryl-acrylonitriles, and 3- dimethylamino-1,2-diaryl-propenones are vinylogous three-carbon building blocks that have been shown to readily convert to regiospecifically functionalized pyrroles in 1-2 steps. 3-Dimethylamino-2-arylacrylic acid esters have also been shown to convert to 3-aryl quinolones in 2 steps. The synthetic schemes and reaction scope are presented as follows.
Crawford, Evan, "Applications of vinylogous 3-carbon building blocks to the synthesis of highly-functionalized nitrogen containing heterocycles" (2018). Honors Theses. 1301.