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Date of Award
2024
Document Type
Restricted Thesis: Campus only access
Degree Name
Bachelor of Science
Department
Chemistry
First Advisor
Dr. Julie A. Pollack
Abstract
MEMO1 is a redox active protein that was initially identified through its interaction with the ErbB2 receptor. While MEMO1 interactions with the ErbB2 receptor have been well characterized, a comprehensive understanding of additional binding partners remains elusive. We have optimized the incorporation of a photo-activatable unnatural amino acid, pBpf, into MEMO1 protein. This modified MEMO1 protein will allow us to identify and isolate MEMO1 protein-protein interactions in breast cancer cell lysates.
Recommended Citation
Mecorapaj, Sonia, "Incorporation of an unnatural amino acid (pBpf) into MEMO1 protein for studying protein-protein interactions" (2024). Honors Theses. 1740.
https://scholarship.richmond.edu/honors-theses/1740