Location

University of Richmond, Richmond, Virginia

Document Type

Poster

Description

We will be characterizing and analyzing properties related to neurite outgrowth, including neurite length & mitochondrial dynamics, in order to understand how MYO19 activity and mitochondrial distribution play a role in neurite development. We aim to observe if loss of MYO19 expression alters these properties, and if reintroducing specific aspects of MYO19 function can “rescue” any observed defects in cells where normal MYO19 expression has been lost. Our studies and hypothesis are based on the previous work of Dr. Quintero and his students, where they have observed differences in the behavior of neuron-like CAD cells when MYO19 expression has been altered.

Comments

Department: Biology Faculty Mentor: Dr. Omar Quintero

Included in

Biology Commons

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Characterization of a MYO19 knockdown phenotype in a cultured neuron-like cell line

University of Richmond, Richmond, Virginia

We will be characterizing and analyzing properties related to neurite outgrowth, including neurite length & mitochondrial dynamics, in order to understand how MYO19 activity and mitochondrial distribution play a role in neurite development. We aim to observe if loss of MYO19 expression alters these properties, and if reintroducing specific aspects of MYO19 function can “rescue” any observed defects in cells where normal MYO19 expression has been lost. Our studies and hypothesis are based on the previous work of Dr. Quintero and his students, where they have observed differences in the behavior of neuron-like CAD cells when MYO19 expression has been altered.