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Date of Award
4-30-2021
Document Type
Restricted Thesis: Campus only access
Degree Name
Bachelor of Science
Department
Biochemistry & Molecular Biol.
First Advisor
Dr. Dominique E. Williams
Abstract
A large obstacle to increasing the efficacy of antibiotics is bacterial biofilm formation. In this study, we sought to develop a strategy to increase the efficacy of antibiotics by measuring how the Ce3+ ion affects both biofilm formation and motility of Pseudomonas putida (P. putida) in the presence of three different carbon-energy sources: 2-phenylethanol, glucose, and citrate. Biofilm formation was characterized via crystal violet-binding assay, and P. putida motility was studied via a swimming assay. The results of the swimming assay were inconclusive, however, while we were unable to test 2-phenylethanol, Ce3+ was found to decrease the formation of biofilm in the presence of citrate and increase biofilm formation in the presence of glucose.
Recommended Citation
Breaux, Emily Marie, "The effect of Ce3+ on Pseudomonas Putida motility and biofilm formation" (2021). Honors Theses. 1593.
https://scholarship.richmond.edu/honors-theses/1593