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Date of Award
Restricted Thesis: Campus only access
Bachelor of Science
Dr. Julie Pollock
MEMO1 is a protein found in high levels in aggressive breast cancers and plays a role in breast cancer cell proliferation and metastasis upon binding to the ErbB2-derived peptide. Previously in the Pollock lab, small molecules that are capable of binding to MEMO1 and disrupting its interactions with other proteins were identified and characterized using fluorescence polarization assays. Building upon this idea, this paper introduces the synthesis of phenazine derivatives as MEMO1 inhibitors and as potential drugs for breast cancer.
Zhou, Ruoxi Lucy, "Synthesis of Modulators of the MEMO1 Protein- Phenazine Derivatives" (2021). Honors Theses. 1535.
Available for download on Saturday, June 13, 2026