Date of Award
2020
Document Type
Thesis
Degree Name
Bachelor of Science
Department
Chemistry
First Advisor
Dr. Miles Johnson
Abstract
Palladium-catalyzed cross-coupling reactions provide an efficient pathway to a wide variety of otherwise inaccessible compounds. In this study, the synthesis and reactivity of novel palladium proazaphosphatrane complexes that are believed to be intermediates in C–N cross-coupling reactions are described. Both the fundamental reactivity of these complexes and elementary steps involved in a catalytic process are demonstrated. The catalytic viability of palladium proazaphosphatrane complexes is shown through stoichiometric and catalytic cross-coupling reactions. Our findings support the long-standing hypothesis that proazaphosphatranes are conformationally flexible ligands that stabilize a number of catalytic intermediates.
Recommended Citation
Matthews, Adrian D., "Synthesis, Characterization, and Reactivity of Palladium Proazaphosphatrane Complexes" (2020). Honors Theses. 1500.
https://scholarship.richmond.edu/honors-theses/1500