Date of Award
Bachelor of Science
Linda Boland, Ph.D.
Due to the large variety of K† channel families implicated in cancer cell proliferation, it is desirable to develop techniques capable of quickly and reliably screening a variety of potential channels for a role in proliferation. While there are many established cell counting procedures, the time-consuming nature of such protocols limits their usefulness in broadly identifying particular channels in uncharacterized cell lines. For this reason, a primary goal of the present research was the development of techniques capable of implicating particular ion channels in proliferation with both qualitative and quantitative data. Once this goal was accomplished, the project sought to conduct preliminary investigations into the role of potassium channels in PEG cell proliferation using the developed techniques.
Foster, Sean, "Development of proliferation assays to explore the role of calcium activated potassium channels in cell proliferation" (2006). Honors Theses. 1041.