Date of Award
4-29-2022
Document Type
Thesis
Degree Name
Bachelor of Science
Department
Chemistry
First Advisor
Miles Johnson
Abstract
Our laboratory has reported the synthesis and characterization of a broad library of unsymmetrical bidentate bis(phosphino)pyrrole (BPP) ancillary ligands for use in nickel-catalyzed cross-coupling reactions. The electronic and steric properties of nickel complexes bearing these ligands are examined, and our data support the hypothesis that these ligands produce nickel complexes with electron-deficient metal centers. The syntheses of (BPP)Ni(o-tolyl)Cl precatalysts for utilization in nickel-catalyzed Buchwald-Hartwig Amination are described, and preliminary reactivity studies reveal that (BPP)Ni(o-tolyl)Cl precatalysts are effective in promoting C–N cross-coupling reactions. Finally, we report steric measurements and electronic properties obtained from computed (BPP)NiCl2 and (BPP)Ni(CO)2 complexes, respectively. Additional reactivity studies to correlate changes in ancillary ligand characteristics with success in nickel catalysis are underway.
Recommended Citation
Vidlak, Julia F., "Synthesis and Study of Unsymmetrical Bidentate Bis(phosphino)pyrrole Ligands and Their Transition Metal Complexes" (2022). Honors Theses. 1650.
https://scholarship.richmond.edu/honors-theses/1650