Abstract
The ability to reproduce is dependent upon proper development of the germline. In male Mus musculus, germline development involves male germ cells (MGCs) differentiating into spermatogonial stem cells (SSCs), the precursors for male gametes. During this differentiation period, MGCs enter a quiescent phase (G0), an essential stage for SSC development. This G0 phase accompanies changes in transcription as well as chromatin accessibility and re-methylation of DNA.
Recommended Citation
Friedman, Kayla; Hatkevich, Talia; and Capel, Blanche
(2022)
"Heterogeneity of RNA-Binding Protein DND1 in G0 Male Germ Cells may Provide a Selection Process for Spermatogonial Stem Cell Development,"
Osmosis Magazine: Vol. 2022:
Iss.
2, Article 8.
Available at:
https://scholarship.richmond.edu/osmosis/vol2022/iss2/8
