Alex Jordan

Date of Award

Summer 1969

Document Type


Degree Name

Master of Arts




The effects of estradiol on RNA, DNA, and protein concentrations in the liver of Natrix fasciata (southern banded water snake) were investigated. Nucleic acid and protein concentrations were determined spectrophotometrically and expressed as mg/gm wet weight tissue.

Significant increases in both RNA and protein occured 48 hours after a single injection of estradiol. After 72 hours the mean RNA level in estradiol treated snakes had decreased significantly from the 48 hour level. The mean protein level at 72 hours, although lower than the 48 hour level, did not decrease significantly.

Liver DNA concentrations in experimental and control snakes were the same through 48 hours. At 72 hours DNA levels in estradiol treated snakes were significantly higher than untreated snakes.

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