Off-campus University of Richmond users: To download campus access theses, please use the following link to log in to our proxy server with your university username and password.


Brian Foster

Date of Award


Document Type

Restricted Thesis: Campus only access

Degree Name

Bachelor of Science



First Advisor

Dr. Suzanne O'Handley


This honors thesis explains my biochemistry research on the NUDIX Hydrolase family of enzymes. In three and a half years, I have worked in Dr. Suzanne O'Handley's lab group on three separate projects, all of them focusing on different enzymes of the NUDIX family. This thesis begins with a general introduction to NUDIX Hydrolases and then is separated into three sections, one for each project I worked on. The three sections include: 1) Orf135, 2) NTPA, and 3) Rv3908 and Rv2985. Each section will contain its own abstract, introduction, materials and methods, and results. The thesis will end with a general conclusion.