Past human genetic diversity and migration between southern China and Southeast Asia have not been well characterized, in part due to poor preservation of ancient DNA in hot and humid regions. We sequenced 31 ancient genomes from southern China (Guangxi and Fujian), including two ∼12,000- to 10,000-year-old individuals representing the oldest humans sequenced from southern China. We discovered a deeply diverged East Asian ancestry in the Guangxi region that persisted until at least 6,000 years ago. We found that ∼9,000- to 6,000-year-old Guangxi populations were a mixture of local ancestry, southern ancestry previously sampled in Fujian, and deep Asian ancestry related to Southeast Asian Hòabìnhian hunter-gatherers, showing broad admixture in the region predating the appearance of farming. Historical Guangxi populations dating to ∼1,500 to 500 years ago are closely related to Tai-Kadai and Hmong-Mien speakers. Our results show heavy interactions among three distinct ancestries at the crossroads of East and Southeast Asia.
© 2021, Elsevier Inc.
The definitive version is available at: Cell Volume 184, Issue 14, 8 July 2021, Pages 3829-3841.e21
Tianyi Wang, Wei Wang, Guangmao Xie, Zhen Li, Xuechun Fan, Qingping Yang, Xichao Wu, Peng Cao, Yichen Liu, Ruowei Yang, Feng Liu, Qingyan Dai, Xiaotian Feng, Xiaohong Wu, Ling Qin, Fajun Li, Wanjing Ping, Lizhao Zhang, Ming Zhang, Yalin Liu, Xiaoshan Chen, Dongju Zhang, Zhenyu Zhou, Yun Wu, Hassan Shafiey, Xing Gao, Darren Curnoe, Xiaowei Mao, E. Andrew Bennett, Xueping Ji, Melinda A. Yang, Qiaomei Fu. "Human population history at the crossroads of East and Southeast Asia since 11,000 years ago," Cell, Volume 184, Issue 14, 2021, 3829-3841.e21, https://doi.org/10.1016/j.cell.2021.05.018.