DOI

10.1093/imammb/dqn002

Abstract

It is known, from both experiments and simulations, that cardiac action potentials are shortened near a nonconducting boundary. In the present paper, this effect is studied in a simple, two-current ionic model, with propagation restricted to a one-dimensional fiber. An asymptotic approximation for the dependence of action potential duration on distance to the boundary is derived. This estimate agrees well with simulations.

Document Type

Post-print Article

Publication Date

2008

Publisher Statement

Copyright © 2008 Oxford University Press.

The definitive version is available at: http://imammb.oxfordjournals.org/content/25/1/21.abstract

DOI: 10.1093/imammb/dqn002

Full Citaiton:

Cain, John W., and David G. Schaeffer. "Shortening of Cardiac Action Potential Duration near an Insulating Boundary." Mathematical Medicine and Biology 25, no. 1 (2008): 21-36. doi:10.1093/imammb/dqn002.

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