Date of Award

1967

Document Type

Thesis

Degree Name

Master of Science

Department

Biology

Abstract

Experiments were conducted to investigate the possibility of the production of interference by ultraviolet inactivated (UVI) Parainfluenza 3 (Para 3) and Echo 21 viruses with active Para 3 and Echo 21 viruses in tissue culture (TC).

Four major experiments were conducted: the effect of UVI Para ~ on active Para 3 in rhesus monkey kidney cell (MKC) tissue culture; the effect of UVI Para 3 on active Para 3 in HEp-2 TC; the effect of UVI Para 3 on Echo 21 in MKC TC; and the effect of UV! Echo 21 on Echo 21 in MKC TC. The rates of production of cytopathic effect {CPE) by active viruses at a ·tissue culture infective dosage of 100% in TC was suppressed to a greater degree by UVI Para 3 and active Echo 21, than when the same virus combinations were used in HEp-2 TC.

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Biology Commons

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