Date of Award
1976
Document Type
Thesis
Degree Name
Master of Science
Department
Chemistry
Abstract
A new scheme is presented for the preparation of 3~(4-chlorophenyl)-5,7-dichloro-l-methylnaphthalene, from which, four derivatives, 3~(4-chlorophenyl)-~-di(n-butyl)aminomethyl~5,7-dichloro-l-naphthalene-methanol hydrochloride, 3-(4-chlorophenyl)-5,7-dichloro-~-(2-piperidyl)-1-naphthalenemethanol acetate, l-[3-(4-chlorophenyl)-5,77dichloro-lnaphthyl]-3-di(n-butyl)aminopropanol hydrochloride, and 1-[3-(4-chlorophenyl)-5, 7-dichloro-l-naph,thyl]-2-(2-piperidyl) ethanol hydrochloride, were prepared. These four derivatives were submitted to Walter Reed Army Institute of Research for. the determination of their potential as antimalarial agents.
Recommended Citation
Shamblee, Dwight Allen, "The synthesis of some potential antimalarials : the 3-(4- choloropheny1) -5, 7- dichloronaphthylaminoalcohols" (1976). Master's Theses. 1051.
https://scholarship.richmond.edu/masters-theses/1051