Date of Award
Master of Arts
Eight adult male albino rats were randomly assigned to each treatment condition of progesterone injections (0,10,40, and ·100 mg/kg/day dissolved in Bee of sesame seed oil), and all 2s received a hypertonic NaCl stomach loading. A control group for procedural effects was given injections of sesame seed oil alone and isotonic NaCl stomach loads. The dependent variables were body weight, food intake and water intake. Single factor analyses of covariance revealed a significant difference between the 0 mg progesterone group and the control group for food and water intake but not weight. No significant differences were found in food and water intake and weight among the four treatment conditions of progesterone. Progesterone does not enhance the efficiency of the male kidney to excrete excess serum solutes but appears to increase the osmotic stressor effect of stomach loading.
Smith, Michael D., "The effect of progesterone on food and water intake and weight in the adult male rats after stomach loads of hypertonic saline" (1973). Master's Theses. 1042.