Off-campus University of Richmond users: To download campus access theses, please use the following link to log in to our proxy server with your university username and password.

Author

Layla Samandi

Date of Award

2016

Document Type

Restricted Thesis: Campus only access

Degree Name

Bachelor of Science

Department

Chemistry

First Advisor

Dr. Kristine Nolin

Abstract

Calcium (II) triflate was found to be an effective Lewis acid catalyst for the inverse electron-demand 1,3-dipolar cycloaddition of nitrones and vinyl ethers. The reaction has been optimized for percent conversion of the reactants to products and the exo to endo product ratio. Exploration of substrate scope is currently underway, with differentially-substituted isoxazolidines produced in fair to good yields with modest diastereoselectivity.

Share

COinS