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Date of Award
Spring 2005
Document Type
Restricted Thesis: Campus only access
Degree Name
Bachelor of Science
Department
Biology
First Advisor
Dr. Krista Fischer-Stenger
Abstract
Previous studies have shown that norepinephrine (NE) can be synthesized, secreted; and taken up by macrophages. This study uses the murine macrophage RAW264.7 cell line as a model to study the effects of NE treatment on macrophage cytolytic activity. Lipopolysaccharide (LPS) is shown to induce macrophage cytolytic activity'in vitro, however results for NE treatment with and without LPS activation of macrophages were inconclusive. These results suggest that NE alters macrophage cytolytic activity, but further studies will need to be done in order to understand the mechanism responsible for these effects.
Recommended Citation
Drake, Lindsey, "The effect of norepinephrine on macrophage cytolytic activity" (2005). Honors Theses. 384.
https://scholarship.richmond.edu/honors-theses/384